DUSP9 anticorps (Middle Region)
Aperçu rapide pour DUSP9 anticorps (Middle Region) (ABIN2788979)
Antigène
Voir toutes DUSP9 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Middle Region
-
Séquence
- SSMAPVPGPV PVVGLGSLCL GSDCSDAESE ADRDSMSCGL DSEGATPPPV
-
Homologie
- Cow: 79%, Dog: 93%, Guinea Pig: 85%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 100%, Yeast: 85%
-
Attributs du produit
- This is a rabbit polyclonal antibody against DUSP9. It was validated on Western Blot.
-
Purification
- Affinity Purified
-
-
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
-
Commentaires
-
Antigen size: 384 AA
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- DUSP9 (Dual Specificity Phosphatase 9 (DUSP9))
-
Autre désignation
- DUSP9
-
Sujet
-
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus.
Alias Symbols: MKP-4, MKP4
Protein Interaction Partner: FAM96B, MAPK11, MAPK14, MMS19, UBC, GSK3B, CDK4, VCP, MAPK3, MAPK1,
Protein Size: 384 -
Poids moléculaire
- 42 kDa
-
ID gène
- 1852
-
NCBI Accession
- NM_001395, NP_001386
-
UniProt
- Q99956
Antigène
-